Technology Search Results

A collaborative effort between researchers at Virginia Tech and Virginia Commonwealth Universities has led to the development of a novel approach for the targeted delivery of imaging and therapeutic agents.

It is well known that the IL-13 Ra2 cell receptor is over-expressed in brain tumors. An IL-13 peptide, known to ...

While tomosynthesis has been studied for decades, interior tomosynthesis is a new concept. This invention was motivated by recent success with interior tomography and compressive sensing. For interior tomosynthesis, a standard medical CT protocol is first executed as routinely done for a patient, which results in a volumetric ...

Bioluminescence has proven to be powerful for investigating biology in vivo. For example, mouse models of tumors with gene expressions tagged by bioluminescence probes have become popular to visualize primary tumor growth, metastasis, and interactions with therapeutic agents and the microenvironment. Bioluminescence tomography (BLT) derives a bioluminescent source distribution ...

Many promising optical molecular imaging modalities, such as bioluminescence tomography (BLT) and fluorescence molecular tomography (FMT) face limitations in detecting deeply embedded optical molecular probes. Based on a biopsy-like optical signal acquisition technique, compressive-sensing-based computational optical biopsy (CSCOB) alleviates the detection depth limitation. CSCOB is minimally invasive to the imaged ...

Novel methods and materials for the delivery of plasmid DNA, oligo DNA, RNA, and other nucleic acids into cells.

The disclosed polymer based materials have been shown to bind and compact nucleic acids into nanoparticles that can be taken up into cells. Additionally, they are endowed with properties ...